Data/hora: 02/06/2024 12:37:38

Provedor de dados: | 19
País: | Japan
Título: | In Vitro Observations on Drug Responsiveness of Babesia bovis and on the Emergence of Drug Resistant Parasites
Autores: | Tan-Ariya, Peerapan; Chetanond, Usa; Brockelman, Charia R.
Data: | 1992-01
Ano: | 1992
Palavras-chave: | Babesia bovis; Drug sensitivity; Drug resistant strain; In vitro microtest; Quinuronium sulfate.
Resumo: | Four culture lines of Babesia bovis Thai strain were successfully established in this study. The results of the in vitro microtest for their sensitivities to quinuronium sulfate revealed that all the culture lines were similarly drug responsive. The 50% inhibitory concentrations for the four culture lines were found to be within the same range, varying from 1.72x10-6 to 2.43x10-6 g/ml. One resistant line TS-2R selected from the drug-treated culture had an IC50 of 1.71x10-5 g/ml which was 7 times higher than that of its original isolate TS-2.
Idioma: | Inglês
Identificador: | http://ir.obihiro.ac.jp/dspace/handle/10322/158
Editor: | Research Center for Protozoan Molecular Immunology
Formato: | application/pdf