Data/hora: 01/06/2024 11:49:20

Provedor de dados: | 19
País: | Japan

Título:

ウマの胃排出能に対するクエン酸モサプリドの促進効果(内科学)

The Prokinetic Effect of Mosapride Citrate on Horse Gastric Emptying Rates(Internal Medicine)

Autores: | OKAMURA, Koichi; SASAKI, Naoki; FUKUNAKA, Morito; YAMADA, Haruo; INOKUMA, Hisashi; 佐々木, 直樹; 猪熊, 壽.
Data: | 2008
Ano: | 2008
Palavras-chave: | Equine; Gastric emptying rate; Mosapride citrate.
Resumo: | The prokinetic effect of the 5-HT4 receptor agonist mosapride was evaluated in seven healthy thoroughbreds. Mosapride was orally administerd at doses of 0.5, 1.0 or 1.5 mg/kg. The breath 13CO2/12CO2 rate (Δ13CO2), an indirect indicator for the rate of gastric empting, was measured at appropriate points for 4 hr after drug administration. There was a significant increase compared with the control value at 15, 20 and 165 min for 0.5 mg/kg, 30 min at 1.0 mg/kg and 165 min for 1.5 mg/kg. The results suggest that mosapride may facilitate the gastric emptying in horses.
Idioma: | Inglês
Identificador: | http://ir.obihiro.ac.jp/dspace/handle/10322/4019
Editor: | 日本獣医学会
Fonte: | 日本獣医学会