Data/hora: 11/06/2024 04:04:51

Provedor de dados: | 19
País: | Japan
Título: | Some Bovine proteins behave as dietary fibres and reduce serum lipids in rats
Autores: | Ruvini, Liyanage; Hashimoto, Naoto; Han, Kyu-Ho; Kajiura, Teppei; Watanabe, Shoko; Shimada, Ken-ichiro; Sekikawa, Mitsuo; Ohba, Kiyoshi; Fukushima, Michihiro.
Data: | 2007
Ano: | 2007
Palavras-chave: | Bovine Dietary proteins; Serum lipids; Dietary Fibres; Hepatic mRNAs.
Resumo: | We examined the physiological importance of bovine dietary proteins in rats fed diets  prepared from bovine Achilles’tendons and arteries. Rats were fed for 4 weeks, with  20% casein diet (CON), in comparison with two diets containing 15% casein and 5% of  either bovine Achilles’ tendons (AC) or arteries (AR) protein preparations. The serum  total cholesterol concentration and non-HDL cholesterol level in the AR fed group were  significantly lower (P&lt;0.05) than those in the CON fed group at the end of the 4 week  feeding period. The hepatic mRNAs were measured, and the HMG-CoA reductase  mRNA level was significantly lower (P&lt;0.05) in AR fed group compared to CON fed  group. Total hepatic cholesterol concentration, in rats fed AC was significantly  (P&lt;0.05) higher than in the CON fed group. The serum triglyceride (TG)  concentration and fatty acid synthase (FAS) mRNA level in AC and AR fed groups were  significantly lower (P&lt;0.05) compared to the CON fed group through out the feeding  period. Faecal neutral sterol excretion was significantly (P&lt;0.05) higher in the AC and  AR fed groups compared to the CON fed group. The results of this study demonstrate  that the some bovine dietary proteins have similar functions as dietary fibres which  lowered the serum lipid concentration by enhancing faecal neutral sterol excretion, or  suppressing lipid synthesis in the liver. Moreover, favourable amino acid compositions  in AR and AC may also have an effect on low plasma lipid concentration in bovine  protein diets fed groups.
Idioma: | Inglês
Identificador: | http://ir.obihiro.ac.jp/dspace/handle/10322/745
Editor: | CABI
Formato: | application/pdf