Data/hora: 11/06/2024 06:28:48

Provedor de dados: 	19	
País: 	Japan	
Título: 	Characterization of a leucine aminopeptidase from Toxoplasma gondii	
Autores: 	Jia, Honglin; Nishikawa, Yoshifumi; Luo, Yuzi; Yamagishi, Junya; Sugimoto, Chihiro; Xuan, Xuenan.	
Data: 	2010-03	
Ano: 	2010	
Palavras-chave: 	Toxoplasma gondii; Leucine aminopeptidase; Enzymatic activity.	
Resumo: 	The M17 family leucine aminopeptidase (LAP) hydrolyze amino acids from the N-terminus of peptides. Many LAPs from parasitic protozoa including Plasmmodium, Trypanosoma and Leishmania, have been intensely investigated because of their crucial roles in parasite biology. In this study, a functional recombinant Toxoplasma gondii LAP (rTgLAP) was expressed in Escherichia coli and its enzymatic activity against synthetic substrates for aminopeptidase, as well as the cellular localization was determined. Our results indicated that TgLAP is a functional aminopeptidase in the cytoplasma of T. gondii.	
Idioma: 	Inglês	
Identificador: 	http://ir.obihiro.ac.jp/dspace/handle/10322/2822	
Editor: 	ELSEVIER	
Formato: 	application/pdf	
Fonte: 	Elsevier B.V.