Data/hora: 13/06/2024 23:13:29

Provedor de dados: 	20	
País: 	Belgium	
Título: 	Polar Alkaloids from the Caribbean Marine Sponge Niphates digitalis	
Autores: 	Regalado, E.L.; Mendiola, J.; Laguna, A.; Nogueiras, C.; Thomas, O.P.	
Data: 	2011-03-02	
Ano: 	2010	
Palavras-chave: 	Sponges; Cytotoxicity; Cytotoxicity; Sponges; Http://aims.fao.org/aos/agrovoc/c_34251; Http://aims.fao.org/aos/agrovoc/c_7321.	
Resumo: 	A method involving flash chromatography, semi-preparative phenylhexyl RP HPLC-DAD-ELSD combined with analytic polar-RP HPLC-DAD, was applied to separate and purify six highly nitrogenated bases and a bicyclic amidine alkaloid, the major components of the marine sponge Niphates digitalis. Their structures were identified as 1,8-diazabicyclo[5.4.0]undec-7- ene (1), deoxycytidine (2), phenylalanine (3), adenosine (4), deoxyguanosine (5), adenine (6) and thymidine (7) on the basis of spectroscopic data analyses. This is the first report of these compounds in a marine sponge belonging to the Niphates genus and the first evidence of the presence of 1 from a natural source.	
Tipo: 	Journal Contribution	
Idioma: 	Inglês	
Identificador: 	Natural Produts Communications, 5(8). p. 1187-1190

http://hdl.handle.net/1834/3860	
Relação: 	http://pubget.com/paper/20839615