Data/hora: 01/06/2024 02:58:15

Provedor de dados: | 3
País: | Brazil
Título: | Evaluation of quantitative parameters of Leydig cell in diabetic adults rats
Autores: | Silva, Alluanan Adelson do Nascimento; Oliveira, Jessica Santana de; Oliveira, Rodrigo Ribeiro de; Moraes, Sílvia Regina Arruda de; Silva Júnior, Valdemiro Amaro da; Melo, Elizabeth Neves de.
Data: | 2014-10-03
Ano: | 2014
Palavras-chave: | 2.00.00.00-6; 2.06.00.00-3 streptozotocin; Testes; Interstitial cells; Morphometry Morfofisiologia Animal.
Resumo: | The goal of present study was to evaluate the effects of diabetes on quantitative parameters of Leydig cells. Twelve adults Wistar rats were divided in: 1) Diabetic Group (DG), which was induced by a single intraperitoneal injection of streptozotocin (60 mg kg-1 of body weight); and 2) Control Group (CG), which received citrate buffer intraperitoneal. After eight weeks of diabetic induction, the animals were weighted, anesthetized and testicles were removed and routinely processed to paraffin embedded. Body weight (40%) and testicular weight (18%) of diabetic rats were significantly lower than control group.  Diabetic rats showed an increase in interstitial compartment but the tubular compartment did not differ. The individual volume of Leydig cells and nuclear diameter were lower in DG. However, the population of these cells was increased. In conclusion, diabetes induced by streptozotocin in adult rats promoted alterations in testicular compartments and changes on volume, nuclear diameter and population of Leydig cells, compromising the testicular function.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês

Identificador:

http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22455

10.4025/actascibiolsci.v36i4.22455

Editor: | Universidade Estadual De Maringá
Relação: | http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/22455/13618
Formato: | application/pdf

Fonte:

Acta Scientiarum. Biological Sciences; v. 36, n. 4 (2014); 483-489

Acta Scientiarum. Biological Sciences; v. 36, n. 4 (2014); 483-489

1807-863X

1679-9283