Data/hora: 18/06/2024 14:12:08

Provedor de dados: | 36
País: | Brazil
Título: | Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei Hook. f.
Autores: | Silva,Ellen Cristina Costa da; Amorim,Rodrigo César das Neves; Tadei,Wanderli Pedro; Pohlit,Adrian Martin.
Data: | 2009-03-01
Ano: | 2009
Palavras-chave: | Caferana; Simaroubaceae; Quassinoid; Recrystallization.
Resumo: | Quassinoids neosergeolide and isobrucein B, obtained from Picrolemma sprucei, have proven in vitro antitumor, antimalarial, anthelminthic, cytotoxic, insecticide and leishmanicidal activities. There is interest in the in vivo pharmacological study of these natural compounds and their semi-synthetic derivatives, however, the quantities obtained in previous extraction processes have been shown to be a limiting factor for continuation of these studies. Herein, we describe a method for obtaining grams of these quassinoids whose purification relies only on recrystallization.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000100026
Editor: | Instituto Nacional de Pesquisas da Amazônia
Relação: | 10.1590/S0044-59672009000100026
Formato: | text/html
Fonte: | Acta Amazonica  v.39 n.1 2009
Fonte: | info:eu-repo/semantics/openAccess