Data/hora: 12/06/2024 05:45:53

Provedor de dados: 	36	
País: 	Brazil	
Título: 	Gram-scale isolation of isobrucein B and neosergeolide from Picrolemma sprucei Hook. f.	
Autores: 	Silva,Ellen Cristina Costa da; Amorim,Rodrigo César das Neves; Tadei,Wanderli Pedro; Pohlit,Adrian Martin.	
Data: 	2009-03-01	
Ano: 	2009	
Palavras-chave: 	Caferana; Simaroubaceae; Quassinoid; Recrystallization.	
Resumo: 	Quassinoids neosergeolide and isobrucein B, obtained from Picrolemma sprucei, have proven in vitro antitumor, antimalarial, anthelminthic, cytotoxic, insecticide and leishmanicidal activities. There is interest in the in vivo pharmacological study of these natural compounds and their semi-synthetic derivatives, however, the quantities obtained in previous extraction processes have been shown to be a limiting factor for continuation of these studies. Herein, we describe a method for obtaining grams of these quassinoids whose purification relies only on recrystallization.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672009000100026	
Editor: 	Instituto Nacional de Pesquisas da Amazônia	
Relação: 	10.1590/S0044-59672009000100026	
Formato: 	text/html	
Fonte: 	Acta Amazonica  v.39 n.1 2009	
Fonte: 	info:eu-repo/semantics/openAccess