Data/hora: 01/06/2024 09:46:41

Provedor de dados: 	42	
País: 	Brazil	
Título: 	Voltammetric characteristics of miconazole and its cathodic stripping voltammetric determination	
Autores: 	PEREIRA,FRANCISCO C.; STRADIOTTO,NELSON R.; ZANONI,MARIA VALNICE B.	
Data: 	2002-09-01	
Ano: 	2002	
Palavras-chave: 	Miconazole; Voltammetry; Electroanalysis; Determination.	
Resumo: 	Miconazole is reduced at mercury electrode above pH 6 involving organometallic compound formation, responsible for an anomalous polarographic behavior. The electrodic process presents a large contribution of the adsorption effects. The drug can be determined by cathodic stripping voltammetry from 8.0 x 10-8 to 1, 5 x 10-6 molL-1 in Britton-Robinson buffer pH 8.0, when pre-accumulated for 30s at an accumulation potential of 0V. A relative standard deviation of 3.8% was obtained for ten measurements of 1.0 x 10-7 molL-1 miconazole in B-R buffer pH 8.0 and a limit detection of 1, 7 x 10-8 molL-1 was determined using 60s of deposition time and scan rate of 100 mVs-1. The proposed method is simple, precise and it was applied successfully for the determination of the miconazole in pure form and in commercial formulations, showing mean recoveries of 99.7-98.4%.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300005	
Editor: 	Academia Brasileira de Ciências	
Relação: 	10.1590/S0001-37652002000300005	
Formato: 	text/html	
Fonte: 	Anais da Academia Brasileira de Ciências  v.74 n.3 2002	
Fonte: 	info:eu-repo/semantics/openAccess