Data/hora: 09/06/2024 15:30:38

Provedor de dados: | 42
País: | Brazil
Título: | Meniscal allograft transplantation in rabbit
Autores: | VILELA,LIANA M.; CARLO,RICARDO J. DEL; Melo FILHO,EDSON V.; FAVARATO,LUKIYA S.C.; DUARTE,TATIANA S.; PONTES,KELLY C.S.; CUNHA,DAISE N.Q.
Data: | 2015-12-01
Ano: | 2015
Palavras-chave: | Knee; Meniscal allograft; Survival analysis; Transplantation; Revascularization.
Resumo: | This study evaluated the technique for meniscal allograft transplantation using allografts preserved in glycerin 98% in rabbits. Euthanasia was performed at 70 days to compare the transplanted (TM1 to TM16) versus the contralateral meniscus (OM1 to OM16). Sixteen menisci, 8 transplanted and 8 contralateral, were submitted to gross examination, histomorphometric analysis for identification and quantification of cellular type, and for quantification and distribution of collagen fibers. A revascularization study was conducted in all of the other samples. Lengths of the OM varied from 0.9 to 1.0 cm and two TM were smaller. All TM were completely attached to the synovial membrane, except for one case that presented partial fixation. Both, TM and OM had similar amounts of chondrocytes, fibroblasts and fibrocytes, and at the horns, chondrocytes were predominant. The collagen fibers in TM were well organized throughout the body, and disorganized at the horns. These fibers in OM were organized. The amounts of collagen type I and III, and the vascularization of the perimeniscal tissue and of the edge were similar in OM and TM. These results demonstrated graft integration and thus this transplantation technique and preservation method may be recommended.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000502205
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201520140417
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.87 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess