Data/hora: 01/06/2024 06:31:47

Provedor de dados: | 42
País: | Brazil
Título: | S-(+)- and R-(-)-linalool: a comparison of the in vitro anti-Aeromonas hydrophila activity and anesthetic properties in fish
Autores: | SILVA,LENISE L.; BALCONI,LUANA S.; GRESSLER,LETÍCIA T.; GARLET,QUELEN I.; SUTILI,FERNANDO J.; VARGAS,AGUEDA P. C.; BALDISSEROTTO,BERNARDO; MOREL,ADEMIR F.; HEINZMANN,BERTA M.
Data: | 2017-03-01
Ano: | 2017
Palavras-chave: | Anesthesia; Aeromonas hydrophila; Chirality; Linalool; Silver catfish.
Resumo: | ABSTRACT Linalool is the main compound of many essential oils and occurs in two isomeric forms: S-(+)- and R-(-)-linalool. This study aimed to determine if linalool isomers have different antimicrobial and anesthetic properties in fish. For this purpose, these compounds were previously isolated from Lippia alba (Mill.)N. E. Brown and Ocimum americanum L. essential oils. Antimicrobial effects were evaluated through the microdilution test against Aeromonas hydrophila, an important fish disease etiologic agent. Induction time until sedation, anesthesia and recovery time were determined in silver catfish (Rhamdia quelen) through bath exposure (60, 180, 300 or 500 μL L-1). The results showed different biological properties for the isomers being S-(+)-linalool the only active against A. hydrophila at 3.2 mg mL-1. The sedation was induced without differences between the compounds, however R-(-)-linalool promoted faster anesthesia. There were no differences regarding the recovery time of the animals exposed to the linalool isomers. Although both S-(+)- and R-(-)-linalool can be used for sedative purposes, their use in A. hydrophila infection is inadvisable due to the high effective concentration. Considering anesthesia as the main objective, the R-(-)-linalool demonstrated clear advantages at lower concentration.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100203
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201720150643
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.89 n.1 2017
Fonte: | info:eu-repo/semantics/openAccess