Data/hora: 09/06/2024 10:22:35

Provedor de dados: | 42
País: | Brazil
Título: | Electrospun novel nanocomposite comprising polyurethane integrated with ayurveda amla oil for bone tissue engineering
Autores: | JAGANATHAN,SARAVANA KUMAR; MANI,MOHAN P.
Data: | 2020-01-01
Ano: | 2020
Palavras-chave: | Polyurethane; Ayurveda oil; Electrospun scaffold; Blood compatibility; Bone tissue engineering.
Resumo: | Abstract  Ayurveda oil contains numerous source of biological constituents which plays an important role in reducing the pain relief caused during bone fracture. The aim of the study is to fabricate the polyurethane (PU) scaffold for bone tissue engineering added with ayurveda amla oil using electrospinning technique. Scanning Electron Microscopy (SEM) analysis showed that the fabricated nanocomposites showed reduced fiber diameter (758 ± 185.46 nm) than the pristine PU (890 ± 116.91 nm). Fourier Infrared Analysis (FTIR) revealed the existence of amla oil in the PU matrix by hydrogen bond formation. The contact angle results revealed the decreased wettability (116° ± 1.528) of the prepared nanocomposites compared to the pure PU (100° ± 0.5774). The incorporation of amla oil into the PU matrix improved the surface roughness. Further, the coagulation assay indicated that the addition of amla oil into PU delayed the blood clotting times and exhibited less toxic to red blood cells. Hence, the fabricated nanocomposites showed enhanced physicochemical and better blood compatibility parameters which may serve as a potential candidate for bone tissue engineering.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000101101
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765202020180369
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.92 n.1 2020
Fonte: | info:eu-repo/semantics/openAccess