Data/hora: 11/06/2024 15:37:29

Provedor de dados: | 42
País: | Brazil
Título: | Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content
Autores: | MONTON,CHAOWALIT; MADAKA,FAMEERA; SETTHARAKSA,SUKANYA; WUNNAKUP,THANIYA; SUKSAEREE,JIRAPORNCHAI; SONGSAK,THANAPAT.
Data: | 2019-01-01
Ano: | 2019
Palavras-chave: | Cannabis sativa; Cannabidiol; Δ9-tetrahydrocannabinol; Optimization.
Resumo: | Abstract: The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively. The three responses (i.e., extraction yield, cannabidiol content, and Δ9- tetrahydrocannabinol content) were predicted by computer software. The yield was high when cannabis was macerated using ethanol at high temperature and long duration time. While cannabidiol and Δ9- tetrahydrocannabinol content was high when macerating at a low heating temperature and short duration time. The optimal condition provided the simultaneous high of cannabidiol and Δ9- tetrahydrocannabinol content was 40 °C for 30 min. The prediction was accurate due to low percent error. This optimal condition could be used as a guide for maceration of cannabis to obtain the extract containing a high content of cannabidiol and Δ9- tetrahydrocannabinol.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000500809
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201920190676
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.91 n.3 2019
Fonte: | info:eu-repo/semantics/openAccess