Data/hora: 06/06/2024 03:47:30

Provedor de dados: | 42
País: | Brazil
Título: | Hepatoprotective, cardioprotective, and renal-protective effects of organic and conventional grapevine leaf extracts (Vitis labrusca var. Bordo) on Wistar rat tissues
Autores: | Oliboni,Lívia S.; Dani,Caroline; Funchal,Cláudia; Henriques,João A.; Salvador,Mirian.
Data: | 2011-12-01
Ano: | 2011
Palavras-chave: | Antioxidant activity; Grapevine leaves; Hepatoprotective; Cardioprotective; Renal-protective; Vitis labrusca.
Resumo: | The purpose of this study was to evaluate the beneficial effects of organic and conventional grapevine (Vitis labrusca L.) leaf extracts in reducing hydrogen peroxide-induced stress in the liver, heart and kidney of Wistar rats by measuring lipids and proteins damages (carbonyl assay), as well as the activity of the antioxidant enzymes superoxide dismutase and catalase. The preincubation with 5 mg/mL of organic and conventional grapevine (Vitis labrusca L.) leaf extracts prevented both lipids and proteins oxidative damages in all tissues analyzed. The organic leaf extract was able to restore superoxide dismutase (kidney and liver) and catalase (heart) activities, which were modified by the treatment with H2O2. The conventional extract was able to restore only the catalase activity in liver and heart tissues. The beneficial effects of the V labrusca leaf extract shown in this study could probably be important for formulating dietary supplements, as well as for developing new ingredients with improved antioxidant properties from other plant sources.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652011000400027
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/S0001-37652011000400027
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.83 n.4 2011
Fonte: | info:eu-repo/semantics/openAccess