Data/hora: 06/06/2024 02:42:18

Provedor de dados: | 42
País: | Brazil
Título: | Bone turnover markers for early detection of fracture healing disturbances: A review of the scientific literature
Autores: | Sousa,Cristina P.; Dias,Isabel R.; Lopez-peña,Mónica; Camassa,José A.; Lourenço,Paulo J.; Judas,Fernando M.; Gomes,Manuela E.; Reis,Rui L.
Data: | 2015-06-01
Ano: | 2015
Palavras-chave: | Bone formation markers; Bone resorption markers; Delayed union; Fracture healing; Osteoclast regulatory proteins; Non-union process.
Resumo: | Imaging techniques are the standard method for assessment of fracture healing processes. However, these methods are perhaps not entirely reliable for early detection of complications, the most frequent of these being delayed union and non-union. A prompt diagnosis of such disorders could prevent prolonged patient distress and disability. Efforts should be directed towards the development of new technologies for improving accuracy in diagnosing complications following bone fractures. The variation in the levels of bone turnover markers (BTMs) have been assessed with regard to there ability to predict impaired fracture healing at an early stage, nevertheless the conclusions of some studies are not consensual. In this article the authors have revised the potential of BTMs as early predictors of prognosis in adult patients presenting traumatic bone fractures but who did not suffer from osteopenia or postmenopausal osteoporosis. The available information from the different studies performed in this field was systematized in order to highlight the most promising BTMs for the assessment of fracture healing outcome.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000201049
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201520150008
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.87 n.2 2015
Fonte: | info:eu-repo/semantics/openAccess