Data/hora: 10/06/2024 14:17:22

Provedor de dados: | 42
País: | Brazil
Título: | In vitro and cellular activities of the selected fruits residues for skin aging treatment
Autores: | LOURITH,NATTAYA; KANLAYAVATTANAKUL,MAYUREE; CHAIKUL,PUXVADEE; CHANSRINIYOM,CHAISAK; BUNWATCHARAPHANSAKUN,PICHAPORN.
Data: | 2017-05-01
Ano: | 2017
Palavras-chave: | Agro-industrial waste; Antioxidant; Cellular activities; Cosmetics; Enzyme inhibitions; Fruit crop.
Resumo: | ABSTRACT Peel extracts of litchi and rambutan, and that of tamarind seed coat were investigated in relation to their utility in skin-aging treatments. Standardized extracts of tamarind were significantly (p &lt; 0.05) more efficient at O2 •- scavenging (IC50 = 27.44 ± 0.09) than those of litchi and rambutan (IC50 = 29.57 ± 0.30 and 39.49 ± 0.52 μg/ml, respectively) and the quercetin standard (IC50 = 31.88 ± 0.15 μg/ml). Litchi extract proved significantly (p &lt; 0.05) more effective for elastase and collagenase inhibition (88.29 ± 0.25% and 79.46 ± 0.92%, respectively) than tamarind (35.43 ± 0.68% and 57.69 ± 5.97%) or rambutan (31.08 ± 0.38% and 53.99 ± 6.18%). All extracts were safe to human skin fibroblasts and inhibit MMP-2, with litchi extract showing significantly (p &lt; 0.01) enhanced inhibition over the standard, vitamin C (23.75 ± 2.74% and 10.42 ± 5.91% at 0.05 mg/ml, respectively). Extracts suppress melanin production in B16F10 melanoma cells through inhibition of tyrosinase and TRP-2, with litchi extract being the most potent, even more so than kojic acid (standard). These results highlight the potential for adding value to agro-industrial waste, as the basis for the sustainable production of innovative, safe, anti-aging cosmetic products.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200577
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201720160849
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.89 n.1 suppl.0 2017
Fonte: | info:eu-repo/semantics/openAccess