Data/hora: 02/06/2024 09:58:21

Provedor de dados: | 42
País: | Brazil
Título: | India ink induces apoptosis in the yellow clam Mesodesma mactroides (Deshayes, 1854). Optical and ultrastructural study
Autores: | CARVALHO,YURI B.M.; JETHRO,JUAN; POERSCH,LUIS H.; ROMANO,LUIS A.
Data: | 2015-12-01
Ano: | 2015
Palavras-chave: | India ink; Inflammation process; Endoplasmic reticulum stress; Apoptosis; Mesodesmama mactroides.
Resumo: | ABSTRACT This paper reports on the acute inflammatory and cellular process in the yellow clam, Mesodesma mactroides, induced by injection of India ink into the muscular foot. Histological observations with optical and electronic microscopy were made at 24 and 48 h after injection. The induced cellular inflammatory response consisted of a general hemocyte infiltration without necrosis and apoptotic activity. Migration of ink-laden phagocytes across the intestinal epithelium was recorded. It appeared that the yellow clam "excreted" ink particles through the gill and kidney. The positive staining for apoptosis was observed in the digestive gland. Electronic microscopy revealed ultrastructural changes of endoplasmic reticulum stress and apoptotic bodies in the digestive gland. The mechanism by which the India ink particles induce apoptosis remains unknown, but might possibly be associated with the endoplasmic reticulum stress. This work has highlighted features that require further discussion in the restricted field the inflammatory responses of mollusks.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000501981
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765201520140600
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.87 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess