Data/hora: 07/06/2024 04:36:06

Provedor de dados: 	42	
País: 	Brazil	
Título: 	Histological evaluation of the periodontal ligament from aged wistar rats supplemented with ascorbic acid	
Autores: 	Zanoni,Jacqueline N.; Lucas,Nathalia M.; Trevizan,Aline R.; Souza,Ivan D.S.	
Data: 	2013-03-01	
Ano: 	2013	
Palavras-chave: 	Aging; Ascorbic acid; Collagen; Periodontal ligament.	
Resumo: 	Ascorbic acid (AA) is able to neutralize reactive oxygen species and is essential for collagen synthesis. In aging process oxidative stress is elevated. This study aims to investigate the effects of AA supplementation on the periodontal ligament (PL) of rats during aging. Twenty five rats were used and divided into groups: J90 (90-day-old control), E345 (345-day-old control), E428 (428-day-old control), EA345 (345-day-old supplemented with AA from 90-day-old on) and EA428 (428-day-old supplemented with AA from 90-day-old on). We analyzed the thickness, density of fibroblasts and blood vessels and collagen fibers types in the PL. In group J90 there was predominantly type III collagen fibers (87.64%). In animals supplemented with AA, the area filled by type I fibers (group EA345: 65.67%, group EA428: 52.23%) was higher than type III fibers. PL in group EA428 was thicker than the one observed in group E428 (P &lt; 0.05). During natural aging process, AA promoted the maturation of collagen fibers and enhanced angiogenesis in periodontal ligament. One can conclude that the supplementation with AA represented a beneficial factor for the development of PL in aged rats.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000100327	
Editor: 	Academia Brasileira de Ciências	
Relação: 	10.1590/S0001-37652013005000003	
Formato: 	text/html	
Fonte: 	Anais da Academia Brasileira de Ciências  v.85 n.1 2013	
Fonte: 	info:eu-repo/semantics/openAccess