Data/hora: 09/06/2024 04:28:56

Provedor de dados: | 42
País: | Brazil
Título: | In vivo biocompatibility of silicon dioxide nanofilm used as antimicrobial agent on acrylic surface
Autores: | LACERDA-SANTOS,ROGÉRIO; LIMA,ANTONIA BÁRBARA L.; PENHA,ELIZANDRA S. DA; SANTOS,ANTONIELSON DOS; CARVALHO,FABÍOLA G.; PITHON,MATHEUS M.; DANTAS,ANTÔNIO FLÁVIO M.
Data: | 2020-01-01
Ano: | 2020
Palavras-chave: | Biomaterials; Biocompatibility; Dentistry; Inflammation.
Resumo: | Abstract the focus ofthis study was to testthe hypothesisthatthere would be no difference betweenthe biocompatibility of silicon dioxide nanofilms used as antimicrobial agents. Sixty male Wistar rats were divided into 4 groups (n=15): Group C (Control,Polyethylene), Group AR (Acrylic Resin), Group NP (Acrylic Resin coated with NP-Liquid), Group BG (Acrylic Resin coated with Bacterlon).the animals were sacrificed with 7,15 and 30 days and tissues analyzed as regardsthe events of inflammatory infiltrate, edema, necrosis, granulation tissue, mutinucleated giant cells, fibroblasts and collagen. Kruskal-Wallis and Dunn tests was used (P&lt;0.05). Intense inflammatory infiltrate was shown mainly in Groups BG and AR, with significant difference from Control Group inthe time interval of 7days (P=0.004). Necrosis demonstrated significant difference between Group BG and Control Group (P&lt;0.05) inthe time intervals of 7 days. For collagen fibers,there was significant difference betweenthe Control Group and Groups AR and BG inthe time interval of 7 days (P=0.006), and between BG and Control Groups inthe time intervals of 15 days (P=0.010).the hypothesis was rejected. Bacterlon demonstratedthe lowest level, and NP-Liquid Glassthe highest level of tissue compatibility, and best cell repair.the coating with NP-Liquid Glass was demonstrated to be highly promising for clinical use.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652020000100910
Editor: | Academia Brasileira de Ciências
Relação: | 10.1590/0001-3765202020181120
Formato: | text/html
Fonte: | Anais da Academia Brasileira de Ciências  v.92 n.1 2020
Fonte: | info:eu-repo/semantics/openAccess