Data/hora: 03/06/2024 08:08:49

Provedor de dados: | 45
País: | Brazil
Título: | Serum neutralization as a differential serological test for classical swine fever virus and other pestivirus infections
Autores: | Paredes,J.C.M.; Oliveira,E.A.S.; Oliveira,L.G.; Rosa,J.C.A.; Roehe,P.M.
Data: | 1999-10-01
Ano: | 1999
Palavras-chave: | Swine; Classical swine fever; Pestivirus; Serology.
Resumo: | Serum neutralization tests (SN) were performed against classical swine fever virus (CSFV), bovine viral diarrhea virus (BVDV) and border disease virus (BDV) on samples of swine serum collected for screening of antibodies to CSFV, in order to determine the SN value as a differential serological test. Ninety-nine sera out of a sample of 16,664 were positive for antibodies to pestiviruses in an ELISA test which did not distinguish antibodies to different pestiviruses. When submitted to SN, 81 sera were positive for CSFV antibodies only. In 17 sera, crossreactive antibodies to either CSFV, BVDV or BDV were detected. In most of these sera (13 out of 17) the differences between SN titres against the three viruses were not sufficient to estimate which was the most likely antibody-inducing virus. It was concluded that, for the SN to be useful in such differentiation, it is essential to examine a sample which must include a representative number of sera from the same farm where suspect animals were detected. When isolated serum samples are examined, such as those obtained with the sampling strategy adopted here, the SN may give rise to inconclusive results.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09351999000500001
Editor: | Universidade Federal de Minas Gerais, Escola de Veterinária
Relação: | 10.1590/S0102-09351999000500001
Formato: | text/html
Fonte: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.51 n.5 1999
Fonte: | info:eu-repo/semantics/openAccess