Data/hora: 05/06/2024 06:46:35

Provedor de dados: | 45
País: | Brazil
Título: | Ammonia poisoning causes muscular but not liver damage in cattle
Autores: | Antonelli,A.C.; Torres,G.A.S.; Soares,P.C.; Mori,C.S.; Sucupira,M.C.A.; Ortolani,E.L.
Data: | 2007-02-01
Ano: | 2007
Palavras-chave: | Cattle; Ammonia poisoning; Urea; Muscle damage; Liver.
Resumo: | Twelve steers were intraruminally administered a high dose (0.5g/kg BW) of urea to study the damage effect of ammonia poisoning on liver and/or muscles. Blood samples were collected to determine ammonia and activities of gammaGT, AST and CK. Eleven steers were successfully poisoned and treated properly, but one succumbed. Poisoned cattle showed high concentration of ammonia, and higher activities of AST and CK. The higher the ammonia, the greater were the activities of AST (r=0.59) and CK (r=0.61). The correlation between AST and CK was high and significant (r=0.80), but not between AST and gammaGT (r=0.19). The activities of AST and CK were higher after the beginning of the convulsive episodes due to ammonia poisoning. Those results showed that occurred muscle damage instead of liver damage since CK is a typical enzyme from skeletal muscle; AST is found either in skeletal muscle and hepatocytes, while gammaGT is present in hepatic cells.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000100002
Editor: | Universidade Federal de Minas Gerais, Escola de Veterinária
Relação: | 10.1590/S0102-09352007000100002
Formato: | text/html
Fonte: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.59 n.1 2007
Fonte: | info:eu-repo/semantics/openAccess