Data/hora: 11/06/2024 02:11:12

Provedor de dados: | 45
País: | Brazil
Título: | Increased leishmanicidal activity of alveolar macrophages from mature horses with mild equine asthma
Autores: | Lessa,D.A.B.; Alencar,N.X.; Torres Filho,R.A.; Costa,M.F.M.; Fernandes,W.R.; Saraiva,E.M.
Data: | 2019-06-01
Ano: | 2019
Palavras-chave: | Horses; Equine asthma; Alveolar macrophage; Phagocytosis; Leishmania (Viannia) braziliensis.
Resumo: | ABSTRACT Alveolar macrophages (AMs) are an essential part of defense mechanisms within the lungs and their phagocytic activity is important for organ homeostasis. The phagocytic ability of AMs obtained from bronchoalveolar lavage from 17 mature mixed-breed pleasure horses (8 healthy and 9 diagnosed with mild equine asthma) was studied through assays with Leishmania (Viannia) braziliensis promastigotes, which enabled the calculation of a phagocytic index (PI) and a survival index (SI). Results indicate that phagocytic activity of AMs in asthma affected horses is similar to healthy horses, while leishmanicidal activity is significantly increased in horses with asthma.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000300939
Editor: | Universidade Federal de Minas Gerais, Escola de Veterinária
Relação: | 10.1590/1678-4162-10708
Formato: | text/html
Fonte: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.71 n.3 2019
Fonte: | info:eu-repo/semantics/openAccess