Data/hora: 10/06/2024 09:25:13

Provedor de dados: 	45	
País: 	Brazil	
Título: 	Identification of SNP c.-22G&amp;gt;A in the melanophilin gene from a dog with color dilution alopecia: case report	
Autores: 	Santos,L.M.; Messas,N.B.; Palumbo,M.I.P.; Miyasato,L.A.; Leal,P.V.; Martins,T.B.; Ramos,C.A.N.	
Data: 	2017-11-01	
Ano: 	2017	
Palavras-chave: 	Genotyping; Dermatology; Skin diseases; Mendelian inheritance.	
Resumo: 	ABSTRACT Mutant color alopecia is an ectodermical defection of color dilution, characterized by partial alopecia, dry, shine-less hair, and peeling and papule. Melanization damages also occur on the cortical structure of the affected hair. The animals affected have big melanin grains with irregular shape on the basal keratinocytes, also on the hair matrix cells and rod. Therefore, there is not a specific treatment that makes any difference on the syndrome evolution. Although in some animals, it is possible to use weekly showers with benzyl peroxide to reduce seborrhea formation and secondary infections. There is evidence that the condition in dogs is caused by a single nucleotide polymorphism in the gene encoding the melanophilin protein. In the present study the identification of the SNP c.-22G&gt;A in the melanophilin gene of a Dachshund breed dog with clinical and histopathologic evidence of color dilution alopecia is reported.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000601503	
Editor: 	Universidade Federal de Minas Gerais, Escola de Veterinária	
Relação: 	10.1590/1678-4162-9710	
Formato: 	text/html	
Fonte: 	Arquivo Brasileiro de Medicina Veterinária e Zootecnia  v.69 n.6 2017	
Fonte: 	info:eu-repo/semantics/openAccess