Data/hora: 01/06/2024 09:49:55

Provedor de dados: 	47	
País: 	Argentina	
Título: 	Antibacterial activity of lactose-binding lectins from Bufo arenarum skin	
Autores: 	Sánchez Riera,Alicia; Daud,Adriana; Gallo,Adriana; Genta,Susana; Aybar,Manuel; Sánchez,Sara.	
Data: 	2003-04-01	
Ano: 	2003	
Palavras-chave: 	Skin; Lectin; Amphibian; Antibacterial activity.	
Resumo: 	Amphibians respond to microbial infection through cellular and humoral defense mechanisms such as antimicrobial protein secretion. Most humoral defense proteins are synthetized in the skin. In this study we isolated two b-galactoside-binding lectins with molecular weights of 50 and 56 KDa from the skin of Bufo arenarum. These lectins have significant hemagglutination activity against trypsinized rabbit erythrocytes, which was inhibited by galactose-containing saccharides. They are water-soluble and independent of the presence of calcium. The antimicrobial analysis for each lectin was performed. At mmolar concentration lectins show strong bacteriostatic activity against Gram negative bacteria (Escherichia coli K12 4100 and wild strains of Escherichia coli and Proteus morganii) and Gram positive bacteria (Enterococcus faecalis). The antibacterial activity of these lectins may provide an effective defense against invading microbes in the amphibian Bufo arenarum.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452003000100005	
Editor: 	Sociedad Latinoamericana de Microscopía Electrónica.; Centro Regional de Investigaciones Científicas y Tecnológicas (Mendoza, Argentina)	
Formato: 	text/html	
Fonte: 	Biocell  v.27 n.1 2003	
Fonte: 	info:eu-repo/semantics/openAccess