Data/hora: 09/06/2024 12:39:55

Provedor de dados: | 48
País: | Chile
Título: | Protective effect of silk lutein on ultraviolet B-irradiated human keratinocytes
Autores: | Pongcharoen,Sutatip; Warnnissorn,Prateep; Lertkajornsin,Ongart; Limpeanchob,Nanteetip; Sutheerawattananonda,Manote.
Data: | 2013-01-01
Ano: | 2013
Palavras-chave: | Silk lutein; Keratinocytes; UV; Apoptosis.
Resumo: | Carotenoids are efficient antioxidants that are of great importance for human health. Lutein and zeaxanthin are carotinoids present in high concentrations in the human retina which are involved in the photoprotection of the human eye. Lutein may also protect the skin from ultraviolet (UV)-induced damage. The present study investigated the protective effect of lutein extracted from yellow silk cocoons of Bombyx mori on human keratinocytes against UVB irradiation. A human keratinocyte cell line and primary human keratinocytes were used to investigate the UVB protection effects of silk lutein and plant lutein. Silk lutein showed no cytotoxicity to keratinocytes. Treatment with silk lutein prior to UVB irradiation enhanced cell viability and cell proliferation, and reduced cell apoptosis. The protective effects of silk lutein may be superior to those of plant lutein. Silk lutein may have a benefit for protection of keratinocytes against UVB-irradiation.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602013000100006
Editor: | Sociedad de Biología de Chile
Formato: | text/html
Fonte: | Biological Research  v.46 n.1 2013