Data/hora: 07/06/2024 02:59:58

Provedor de dados: | 48
País: | Chile
Título: | 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
Autores: | SANTILLÁN,G; KATZ,S; BUITRAGO,C; BOLAND,R.
Data: | 2004-01-01
Ano: | 2004
Palavras-chave: | CCE TRPC muscle cells osteoblasts 1a; 25(OH)2D3 VDR INAD.
Resumo: | This work describes the involvement of TRPC proteins in capacitative calcium entry (CCE) induced by 1a,25-dihydroxy-vitamin-D3 [1a,25(OH)2D3] in chick skeletal muscle and in rat osteoblast-like cells (ROS 17/2.8) and the role of the vitamin D receptor (VDR) in this non-genomic rapid response mediated by the hormone. We propose that an endogenous TRPC3 protein mediates 1a,25(OH)2D3 modulation of CCE in these cells, which seems to implicate VDR-TRPC3 association and the participation of an INAD-like scaffold protein.
Tipo: | Journal article
Idioma: | Inglês
Identificador: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400021
Editor: | Sociedad de Biología de Chile
Formato: | text/html
Fonte: | Biological Research  v.37 n.4 2004