Data/hora: 06/06/2024 01:21:41

Provedor de dados: 	5	
País: 	France	
Título: 	Chalcogenide Glass Optical Waveguides for Infrared Biosensing	
Autores: 	Anne, Marie-laure; Keirsse, Julie; Nazabal, Virginie; Hyodo, Koji; Inoue, Satoru; Boussard-pledel, Catherine; Lhermite, Herve; Charrier, Joel; Yanakata, Kiyoyuki; Loreal, Olivier; Le Person, Jenny; Colas, Florent; Compere, Chantal; Bureau, Bruno.	
Data: 	2009-09	
Ano: 	2009	
Palavras-chave: 	Planar waveguide; Fibre; Optical sensor; Chalcogenide.	
Resumo: 	Due to the remarkable properties of chalcogenide (Chg) glasses, Chg optical waveguides should play a significant role in the development of optical biosensors. This paper describes the fabrication and properties of chalcogenide fibres and planar waveguides. Using optical fibre transparent in the mid-infrared spectral range we have developed a biosensor that can collect information on whole metabolism alterations, rapidly and in situ. Thanks to this sensor it is possible to collect infrared spectra by remote spectroscopy, by simple contact with the sample. In this way, we tried to determine spectral modifications due, on the one hand, to cerebral metabolism alterations caused by a transient focal ischemia in the rat brain and, in the other hand, starvation in the mouse liver. We also applied a microdialysis method, a well known technique for in vivo brain metabolism studies, as reference. In the field of integrated microsensors, reactive ion etching was used to pattern rib waveguides between 2 and 300 mu m wide. This technique was used to fabricate Y optical junctions for optical interconnections on chalcogenide amorphous films, which can potentially increase the sensitivity and stability of an optical micro-sensor. The first tests were also carried out to functionalise the Chg planar waveguides with the aim of using them as (bio) sensors.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	http://archimer.ifremer.fr/doc/2009/publication-6851.pdf

DOI:10.3390/s90907398	
Editor: 	Molecular Diversity Preservation International-MDPI	
Relação: 	http://archimer.ifremer.fr/doc/00000/6851/	
Formato: 	application/pdf	
Fonte: 	Sensors (1424-8220) (Molecular Diversity Preservation International-MDPI), 2009-09 , Vol. 9 , N. 9 , P. 7398-7411	
Fonte: 	2009 MDPI Publishing