Data/hora: 01/06/2024 01:30:17

Provedor de dados: | 5
País: | France
Título: | Building of an immunosensor: How can the composition and structure of the thiol attachment layer affect the immunosensor efficiency?
Autores: | Briand, Elisabeth; Salmain, Michèle; Henry, Jean-marie; Perrot, Hubert; Compere, Chantal; Pradier, Claire-marie.
Data: | 2006-09
Ano: | 2006
Palavras-chave: | QCM; IRRAS; Thiol attachment; Immunosensor; Mixed SAM' s.
Resumo: | Immunosensors, based on the immobilization of a model rabbit antibody on mixed self-assembled monolayers and Protein A as a linking agent on gold transducers, were elaborated and characterized at each step by modulated polarization-infrared spectroscopy (PM-IRRAS) and occasionally by atomic force microscopy (AFM) and quartz crystal microbalance (QCM). By testing two different mixed SAMs comprising 11-mercaptoundecanoic acid (MUA), together with either decanethiol (C9CH3) or mercaptohexanol (C6OH), the role of the chemical composition and structure of the antibody attachment layer upon the sensor performance was demonstrated. (c) 2006 Elsevier B.V. All rights reserved.
Tipo: | Text
Idioma: | Inglês

Identificador:

http://archimer.ifremer.fr/doc/2006/publication-1988.pdf

DOI:10.1016/j.bios.2006.05.018

Editor: | Elsevier
Relação: | http://archimer.ifremer.fr/doc/00000/1988/
Formato: | application/pdf
Fonte: | Biosensors and Bioelectronics (0956-5663) (Elsevier), 2006-09 , Vol. 22 , N. 3 , P. 440-448
Fonte: | 2006 Elsevier B.V. All rights reserved