Data/hora: 06/06/2024 15:42:15

Provedor de dados: | 5
País: | France
Título: | Cytotoxic and Anti-Inflammatory Effects of Ent-Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia
Autores: | Aimond, Axelle; Calabro, Kevin; Audoin, Coralie; Olivier, Elodie; Dutot, Mélody; Buron, Pauline; Rat, Patrice; Laprévote, Olivier; Prado, Soizic; Roulland, Emmanuel; Thomas, Olivier P.; Genta-jouve, Grégory.
Data: | 2020-02
Ano: | 2020
Palavras-chave: | Sideritis hyssopifolia; Ent-kaurane; Anti-inflammatory; NMR.
Resumo: | This paper reports the isolation and structural characterization of four new ent-kaurane derivatives from the Lamiaceae plant Sideritis hyssopifolia. Planar structures and relative configurations were determined using both mass spectrometry and nuclear magnetic resonance (1D and 2D). Absolute configurations were determined by comparing experimental and theoretical electronic circular dichroism spectra. The cytotoxic and microbial activities of all new compounds were tested. Compounds that were non-cytotoxic were further evaluated for anti-inflammatory activity.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00610/72214/71012.pdf

https://archimer.ifremer.fr/doc/00610/72214/71013.pdf

DOI:10.3390/molecules25030589

https://archimer.ifremer.fr/doc/00610/72214/

Editor: | MDPI AG
Formato: | application/pdf
Fonte: | Molecules (1420-3049) (MDPI AG), 2020-02 , Vol. 25 , N. 3 , P. 589 (10p.)

Fonte:

info:eu-repo/semantics/openAccess

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