Data/hora: 11/06/2024 11:20:49

Provedor de dados: 	5	
País: 	France	
Título: 	Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts	
Autores: 	Twiner, Michael J.; Rehmann, Nils; Hess, Philipp; Doucette, Gregory J.	
Data: 	2008-06	
Ano: 	2008	
Palavras-chave: 	Azaspiracid (AZA); AZP; Shellfish poisoning.	
Resumo: 	Azaspiracids (AZA) are polyether marine toxins that accumulate in various shellfish species and have been associated with severe gastrointestinal human intoxications since 1995. This toxin class has since been reported from several countries, including Morocco and much of western Europe. A regulatory limit of 160 mu g AZA/kg whole shellfish flesh was established by the EU in order to protect human health; however, in some cases, AZA concentrations far exceed the action level. Herein we discuss recent advances on the chemistry of various AZA analogs, review the ecology of AZAs, including the putative progenitor algal species, collectively interpret the in vitro and in vivo data on the toxicology of AZAs relating to human health issues, and outline the European legislature associated with AZAs.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	http://archimer.ifremer.fr/doc/00077/18805/16375.pdf

DOI:10.3390/md20080004	
Editor: 	Molecular Diversity Preservation Int	
Relação: 	http://archimer.ifremer.fr/doc/00077/18805/	
Formato: 	application/pdf	
Fonte: 	Marine Drugs (1660-3397) (Molecular Diversity Preservation Int), 2008-06 , Vol. 6 , N. 2 , P. 39-72	
Fonte: 	2008 MDPI