Data/hora: 15/06/2024 03:09:06

Provedor de dados: | 5
País: | France
Título: | High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii
Autores: | Michoud, Gregoire; Jebbar, Mohamed.
Data: | 2016-06
Ano: | 2016
Resumo: | Pyrococcus yayanosii CH1, as the first and only obligate piezophilic hyperthermophilic microorganism discovered to date, extends the physical and chemical limits of life on Earth. It was isolated from the Ashadze hydrothermal vent at 4,100 m depth. Multi-omics analyses were performed to study the mechanisms used by the cell to cope with high hydrostatic pressure variations. In silico analyses showed that the P. yayanosii genome is highly adapted to its harsh environment, with a loss of aromatic amino acid biosynthesis pathways and the high constitutive expression of the energy metabolism compared with other non-obligate piezophilic Pyrococcus species. Differential proteomics and transcriptomics analyses identified key hydrostatic pressure-responsive genes involved in translation, chemotaxis, energy metabolism (hydrogenases and formate metabolism) and Clustered Regularly Interspaced Short Palindromic Repeats sequences associated with Cellular apoptosis susceptibility proteins.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00342/45295/44756.pdf

https://archimer.ifremer.fr/doc/00342/45295/44757.pdf

https://archimer.ifremer.fr/doc/00342/45295/44758.csv

DOI:10.1038/srep27289

https://archimer.ifremer.fr/doc/00342/45295/

Editor: | Nature Publishing Group
Formato: | application/pdf
Fonte: | Scientific Reports (2045-2322) (Nature Publishing Group), 2016-06 , Vol. 6 , N. 27289 , P. 1-10

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