Data/hora: 10/06/2024 06:43:27

Provedor de dados: | 5
País: | France
Título: | Gluconeogenic enzyme gene expression is decreased by dietary carbohydrates in common carp (Cyprinus carpio) and gilthead seabream (Sparus aurata)
Autores: | Panserat, Stéphane; Plagnes Juan, E; Kaushik, Sadasivam.
Data: | 2002-11
Ano: | 2002
Palavras-chave: | Gilthead seabream; Common carp; Gluconeogenesis; Gene expression; Hepatic glucose metabolism; Dietary carbohydrate.
Resumo: | Our objective is to understand the low metabolic utilization of dietary carbohydrates in fish. We compared the regulation of gluconeogenic enzymes at a molecular level in two fish species, the common carp (Cyprinus carpio) and gilthead seabream (Sparus aurata), known to be relatively tolerant to dietary carbohydrates. After cloning of partial cDNA sequences for three key gluconeogenic enzymes (glucose-6-phosphatase (G6Pase), fructose biphosphatase (FBPase) and phosphoenolpyruvate carboxykinase (PEPCK) in the two species, we analyzed gene expressions of these enzymes 6 and 24 h after feeding with (20%) or without carbohydrates. Our data show that there is at least one gluconeogenic enzyme strongly regulated (decreased expression after feeding) in the two fish species, i.e. the PEPCK for common carp and G6Pase/FBPase for gilthead seabream. In these fish species, the regulation seems to be similar to the mammals at least at the molecular level.
Tipo: | Text
Idioma: | Inglês

Identificador:

http://archimer.ifremer.fr/doc/2002/publication-668.pdf

DOI:10.1016/S0167-4781(02)00501-8

Editor: | Elsevier
Relação: | http://archimer.ifremer.fr/doc/00000/668/
Formato: | application/pdf
Fonte: | Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression (0167-4781) (Elsevier), 2002-11 , Vol. 1579 , N. 1 , P. 35-42
Fonte: | 2002 Elsevier Science B.V. All rights reserved