Data/hora: 02/06/2024 13:35:14

Provedor de dados: | 5
País: | France
Título: | Virus-host coexistence in phytoplankton through the genomic lens
Autores: | Yau, Sheree; Krasovec, Marc; Benites, L. Felipe; Rombauts, Stephane; Groussin, Mathieu; Vancaester, Emmelien; Aury, Jean-marc; Derelle, Evelyne; Desdevises, Yves; Escande, Marie-line; Grimsley, Nigel; Guy, Julie; Moreau, Hervé; Sanchez-brosseau, Sophie; Van De Peer, Yves; Vandepoele, Klaas; Gourbiere, Sebastien; Piganeau, Gwenael.
Data: | 2020-04
Ano: | 2020
Resumo: | Virus-microbe interactions in the ocean are commonly described by “boom and bust” dynamics, whereby a numerically dominant microorganism is lysed and replaced by a virus-resistant one. Here, we isolated a microalga strain and its infective dsDNA virus whose dynamics are characterized instead by parallel growth of both the microalga and the virus. Experimental evolution of clonal lines revealed that this viral production originates from the lysis of a minority of virus-susceptible cells, which are regenerated from resistant cells. Whole-genome sequencing demonstrated that this resistant-susceptible switch involved a large deletion on one chromosome. Mathematical modeling explained how the switch maintains stable microalga-virus population dynamics consistent with their observed growth pattern. Comparative genomics confirmed an ancient origin of this “accordion” chromosome despite a lack of sequence conservation. Together, our results show how dynamic genomic rearrangements may account for a previously overlooked coexistence mechanism in microalgae-virus interactions.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00623/73461/72701.pdf

https://archimer.ifremer.fr/doc/00623/73461/72702.pdf

DOI:10.1126/sciadv.aay2587

https://archimer.ifremer.fr/doc/00623/73461/

Editor: | American Association for the Advancement of Science (AAAS)
Formato: | application/pdf
Fonte: | Science Advances (2375-2548) (American Association for the Advancement of Science (AAAS)), 2020-04 , Vol. 6 , N. 14 , P. eaay2587 (12p.)

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info:eu-repo/semantics/openAccess

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