Data/hora: 10/06/2024 16:21:24

Provedor de dados: | 5
País: | France
Título: | Exploring the chemodiversity of tropical microalgae for the discovery of natural antifouling compounds
Autores: | Réveillon, Damien; Tunin-ley, Alina; Grondin, Isabelle; Othmani, Ahlem; Zubia, Mayalen; Bunet, Robert; Turquet, Jean; Culioli, Gérald; Briand, Jean-françois.
Data: | 2019-02
Ano: | 2019
Palavras-chave: | Microalgae; Antifouling; Bioassay; Chemodiversity; Bioprospecting; Metabolomics.
Resumo: | Marine microalgae and cyanobacteria have largely been studied for their biotechnological potential and proved their ability to produce a wide array of bioactive molecules. We investigated the antifouling potential of unexplored benthic tropical microalgae using anti-adhesion and toxicity bioassays against two major micro- and ma crobiofoulers, namely bacteria and barnacles. Fifty strains belonging to six phyla [Cyanobacteria, Miozoa (Dinoflagellata), Bacillariophyta, Cryptophyta, Rhodophyta and Haptophyta] were isolated from southwestern Islands of the Indian Ocean. They were chosen in order to represent as much as possible the huge biodiversity of such a rich tropical ecosystem. The associated chemodiversity was highlighted by both NMR- and LC-MS-based metabolomics. The screening of 84 algal fractions revealed that the anti-adhesion activity was concentrated in methanolic ones (i.e. 93% of all active fractions). Our results confirmed that microalgae constitute a promising source of natural antimicrofoulants as 17 out of the 30 active fractions showed high or very high capacity to inhibit the adhesion of three biofilm-forming marine bacteria. Dinoflagellate-derived fractions were the most active, both in terms of number and intensity. However, dinoflagellates were also more toxic and may not be suitable as a source of environmentally friendly antifouling compounds, in contrast to diatoms, e.g. Navicula mollis. The latter and two dinoflagellates of the genus Amphidinium also had interesting anti-settlement activities while being moderately toxic to barnacle larvae. Our approach, combining the bioprospecting of a large number of tropical microalgae for their anti-settlement potential and metabolomics analyses, constituted a first step towards the discovery of alternative ecofriendly antifoulants.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00454/56608/58333.pdf

DOI:10.1007/s10811-018-1594-z

https://archimer.ifremer.fr/doc/00454/56608/

Editor: | Springer Nature America, Inc
Formato: | application/pdf
Fonte: | Journal Of Applied Phycology (0921-8971) (Springer Nature America, Inc), 2019-02 , Vol. 31 , N. 1 , P. 319-333

Fonte:

Springer Nature B.V. 2018

info:eu-repo/semantics/openAccess

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