Data/hora: 10/06/2024 15:16:50

Provedor de dados: 	5	
País: 	France	
Título: 	Characterization of GnRH-related peptides from the Pacific oyster Crassostrea gigas	
Autores: 	Bigot, Laetitia; Zatylny-gaudin, Celine; Rodet, Franck; Bernay, Benoit; Boudry, Pierre; Favrel, Pascal.	
Data: 	2012-04	
Ano: 	2012	
Palavras-chave: 	Mollusk; Bivalve; Oyster; Neuroendocrinology; Reproduction; GnRH.	
Resumo: 	Gonadotropin-releasing hormone (GnRH), a key neuropeptide regulating reproduction in vertebrates has now been characterized in a number of non-vertebrate species. Despite the demonstration of its ancestral origin, the structure and the function of this family of peptides remain poorly known in species as distant as lophotrochozoans. In this study, two GnRH-related peptides (Cg-GnRH-a and CgGnRH-G) were characterized by mass spectrometry from extracts of the visceral ganglia of the Pacific oyster Crassostrea gigas. These peptides showed a high degree of sequence identity with GnRHs of other mollusks and annelids and to a lesser extent with those of vertebrates or with AKH and corazonins of insects. Both the mature peptides and the transcript encoding the precursor protein were exclusively expressed in the visceral ganglia. Significant differences in transcriptional activity of Cg-GnRH encoding gene were recorded in the ganglia along the reproductive cycle and according to trophic conditions with a higher level in fed animals compared to starved animals. This suggests the involvement of Cg-GnRHs as synchronizers of nutritional status with energy requirements during reproduction in oyster. Evidence for a role of Cg-GnRHs as neuroregulators and as neuroendocrine factors in bivalve is discussed. (C) 2012 Elsevier Inc. All rights reserved.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	http://archimer.ifremer.fr/doc/00079/19003/17477.pdf

DOI:10.1016/j.peptides.2012.01.017	
Editor: 	Elsevier Science Inc	
Relação: 	http://archimer.ifremer.fr/doc/00079/19003/	
Formato: 	application/pdf	
Fonte: 	Peptides (0196-9781) (Elsevier Science Inc), 2012-04 , Vol. 34 , N. 2 , P. 303-310	
Fonte: 	2012 Elsevier Inc. All rights reserved.