Data/hora: 07/06/2024 01:45:39

Provedor de dados: 	5	
País: 	France	
Título: 	Modélisation de la détoxication de mollusques bivalves contenant des phycotoxines paralysantes ou diarrhéiques

Detoxification modelling of bivalves containing paralytic and diarrhoeic phycotoxins	
Autores: 	Gueguen, Marielle.	
Data: 	2009-10-26	
Ano: 	2009	
Palavras-chave: 	Modélisation; Mytilus edulis; Crassostrea gigas; Phycotoxines; Détoxication; Acide okadaïque; Toxines paralysantes; Modelling; Mytilus edulis; Crassostrea gigas; Phycotoxins; Detoxification; Okadaix acid; Paralytic toxin.	
Resumo: 	The purpose of this study is to implement models to describe detoxification kinetics of Pacific oysters Crassostrea gigas and Blue mussels Mytilus edulis containing paralytic and diarrheic phycotoxins respectively. First, experimental trials made it possible to complement data from the literature regarding the understanding of processes involved in mollusc detoxification. In particular, they pointed out a difference in the mollusc capacity to degrade cellwalls of phycotoxin-producing dinoflagellates, according to their en cystement capacities. It was observed that paralytic phycotoxins reached the various oyster tissues whereas diarrheic toxins were mainly sequestred in the digestive gland of mussels. The latter seem to be retained by lysosomes localized in digestive cells. The influence of intrinsic and extrinsic variables was also demonstrated. Then, the results obtained made it possible to implement various models taking into account transfers between tissues, biotransformations and the influence of environmental variables. It was proved that the detoxification kinetics of oysters containing paralytic toxins can be represented by two-compartment model, representing the digestive gland and the other tissues, the detoxification coefficients depending on environmental variables and on ratios between the various saxitoxin analogues. The detoxification of mussels containing diarrheic toxins can be simulated by a one-compartment model where the detoxification coefficient depends on environmental variables.	
Tipo: 	Text	
Idioma: 	Francês	
Identificador: 	http://archimer.ifremer.fr/doc/00003/11473/8032.pdf	
Editor: 	Université de Nantes	
Relação: 	http://archimer.ifremer.fr/doc/00003/11473/	
Formato: 	application/pdf