Data/hora: 06/06/2024 10:19:19

Provedor de dados: 	5	
País: 	France	
Título: 	Antiviral immunity in marine molluscs	
Autores: 	Green, Timothy J.; Raftos, David; Speck, Peter; Montagnani, Caroline.	
Data: 	2015-09	
Ano: 	2015	
Resumo: 	Marine molluscs, like all living organisms, are constantly exposed to viruses and have evolved efficient antiviral defences. We review here recent developments in molluscan antiviral immunity against viruses belonging to the order Herpesvirales. Emerging results suggest an interferon-like response and autophagy are involved in the antiviral defence of bivalves to viral infection. Multifunctional plasma proteins from gastropods and bivalves have been identified to have broadspectrum antiviral activity against mammalian viruses. The antiviral defences present in molluscs can be enhanced by genetic selection, as shown by the presence of oyster strains specifically resistant to ostreid herpesvirus type 1. Whether varying amounts or different isofornns of these antiviral plasma proteins contributes to genetic resistance is worthy of further research. Other evolutionarily conserved antiviral mechanisms, such as RNA interference and apoptosis, still need further characterization.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	http://archimer.ifremer.fr/doc/00296/40743/39736.pdf

DOI:10.1099/jgv.0.000244

http://archimer.ifremer.fr/doc/00296/40743/	
Editor: 	Soc General Microbiology	
Formato: 	application/pdf	
Fonte: 	Journal Of General Virology (0022-1317) (Soc General Microbiology), 2015-09 , Vol. 96 , P. 2471-2482	
Fonte: 	2015 The Authors | Published by the Microbiology Society

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