Data/hora: 11/06/2024 01:34:14

Provedor de dados: 	5	
País: 	France	
Título: 	Sunscreen, antioxidant, and bactericide capacities of phlorotannins from the brown macroalga Halidrys siliquosa	
Autores: 	Le Lann, Klervi; Surget, Gwladys; Couteau, Celine; Coiffard, Laurence; Cerantola, Stephane; Gaillard, Fanny; Larnicol, Maud; Zubia, Mayalen; Guerard, Fabienne; Poupart, Nathalie; Stiger-pouvreau, Valerie.	
Data: 	2016-12	
Ano: 	2016	
Palavras-chave: 	Antioxidant; Bactericidal; Phenolic compounds; Phaeophyceae; Seaweed; ORAC value; Sunscreen potential.	
Resumo: 	The present study focused on a brown macroalga (Halidrys siliquosa), with a particular emphasis on polyphenols and their associated biological activities. Two fractions were obtained by liquid/liquid purification from a crude hydroethanolic extract: (i) an ethyl acetate fraction and (ii) an aqueous fraction. Total phenolic contents and antioxidant activities of extract and both fractions were assessed by in vitro tests (Folin-Ciocalteu test, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, reducing power assay, superoxide anion scavenging assay, and beta-carotene-linoleic acid system). For the most active fraction, i.e., the ethyl acetate fraction, the oxygen radical absorbance capacity (ORAC) value, antibacterial activities, and sunscreen potential (Sun Protection Factor and UV-A-Protection Factor) were tested in vitro. A high correlation found between antioxidant activities and total phenolic content was interpreted as the involvement of polyphenolic compounds in antioxidant mechanisms. Interestingly, the ethyl acetate fraction appeared to be a broad-spectrum UV absorber and showed a strong bactericidal activity against Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli. In this fraction, four phenolic compounds (trifuhalols and tetrafuhalols and, for the first time, diphlorethols and triphlorethols) were identified using 1D and 2D nuclear magnetic resonance (NMR) and MS analysis. These findings are promising for the use of H. siliquosa, abundant in Brittany, as a valuable source of photoprotectant molecules for sunscreen and cosmetic applications.	
Tipo: 	Text	
Idioma: 	Inglês	
Identificador: 	https://archimer.ifremer.fr/doc/00366/47682/47970.pdf

DOI:10.1007/s10811-016-0853-0

https://archimer.ifremer.fr/doc/00366/47682/	
Editor: 	Springer	
Formato: 	application/pdf	
Fonte: 	Journal Of Applied Phycology (0921-8971) (Springer), 2016-12 , Vol. 28 , N. 6 , P. 3547-3559	
Fonte: 	Springer Science+Business Media Dordrecht 2016

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