Data/hora: 06/06/2024 17:08:54

Provedor de dados: | 5
País: | France
Título: | The Complete Genome Sequence of the Fish Pathogen Tenacibaculum maritimum Provides Insights into Virulence Mechanisms
Autores: | Perez-pascual, David; Lunazzi, Aurelie; Magdelenat, Ghislaine; Rouy, Zoe; Roulet, Alain; Lopez-roques, Celine; Larocque, Robert; Barbeyron, Tristan; Gobet, Angelique; Michel, Gurvan; Bernardet, Jean-francois; Duchaud, Eric.
Data: | 2017-08
Ano: | 2017
Palavras-chave: | Tenacibaculum maritimum; Fish pathogen; Virulence factors; Genome; Toxins.
Resumo: | Tenacibaculum maritimum is a devastating bacterial pathogen of wild and farmed marine fish with a broad host range and a worldwide distribution. We report here the complete genome sequence of the T. maritimum type strain NCIMB 2154(T). The genome consists of a 3,435,971-base pair circular chromosome with 2,866 predicted protein-coding genes. Genes encoding the biosynthesis of exopolysaccharides, the type IX secretion system, iron uptake systems, adhesins, hemolysins, proteases, and glycoside hydrolases were identified. They are likely involved in the virulence process including immune escape, invasion, colonization, destruction of host tissues, and nutrient scavenging. Among the predicted virulence factors, type IX secretion-mediated and cell-surface exposed proteins were identified including an atypical sialidase, a sphingomyelinase and a chondroitin AC lyase which activities were demonstrated in vitro.
Tipo: | Text
Idioma: | Inglês

Identificador:

https://archimer.ifremer.fr/doc/00488/59939/63150.pdf

https://archimer.ifremer.fr/doc/00488/59939/63151.pdf

https://archimer.ifremer.fr/doc/00488/59939/63152.pdf

https://archimer.ifremer.fr/doc/00488/59939/63153.pdf

https://archimer.ifremer.fr/doc/00488/59939/63154.pdf

https://archimer.ifremer.fr/doc/00488/59939/63155.pdf

https://archimer.ifremer.fr/doc/00488/59939/63156.pdf

https://archimer.ifremer.fr/doc/00488/59939/63157.pdf

DOI:10.3389/fmicb.2017.01542

https://archimer.ifremer.fr/doc/00488/59939/

Editor: | Frontiers Media Sa
Formato: | application/pdf
Fonte: | Frontiers In Microbiology (1664-302X) (Frontiers Media Sa), 2017-08 , Vol. 8 , N. 1542 , P. 11p.

Fonte:

info:eu-repo/semantics/openAccess

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