Data/hora: 07/06/2024 08:31:36

Provedor de dados: | 52
País: | Brazil
Título: | Composition and significance of glycosaminoglycans in the uterus and placenta of mammals
Autores: | Oliveira,Gleidson Benevides de; Vale,André Menezes do; Santos,Amílton Cesar dos; Moura,Carlos Eduardo Bezerra de; Rocha,Hugo Alexandre de Oliveira; Oliveira,Moacir Franco de.
Data: | 2015-08-01
Ano: | 2015
Palavras-chave: | Extracellular matrix; Hormonal fluctuation; Reproductive events; Euterium mammals; Pathology.
Resumo: | Glycosaminoglycans (GAGs) are heteropolysaccharides in mammalian tissue and consist of repeated disaccharide units with mono-sulfated or non-sulfated monosaccharides. GAGs are important components of the Extracellular Matrix (ECM) with several physiological roles, in the recognition, migration, adhesion, proliferation and differentiation processes. They are also important in angiogenesis, blood homeostasis, immune reactions, follicule development and also in the development of pathologies such as infertility, tumors and metastases. It has been shown that the profile of glycosaminoglycans in the uterine and placental tissues is highly variable throughout the reproductive cycle and during pregnancy. It may be directly related to their physiological or pathological functions in the tissue. The latter has recently triggered special clinical interest. Current review collaborates for a deeper knowledge on the profile and importance of GAGs in uterine and placental tissues throughout the reproductive cycle and pregnancy. It also covers information on the involvement of these molecules in pathological processes.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000400512
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-8913201500281
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.58 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess