Data/hora: 11/06/2024 05:46:14

Provedor de dados: | 52
País: | Brazil
Título: | Saccharomyces uvarum mannoproteins stimulate a humoral immune response in mice
Autores: | Darpossolo,Fernanda Patrícia Brito; Eto,Silas Fernandes; Venancio,Emerson José; Castro-Goméz,Raul Jorge Hernan.
Data: | 2012-08-01
Ano: | 2012
Palavras-chave: | Glycoprotein; Swiss mice; Antibody production; Yeast; Cell wall.
Resumo: | Yeasts discarded in industrial processes can be used as a nutritional supplement and to extract cellular components with biotechnological aims. In this study, the humoral immune response of Swiss mice treated with mannoproteins (MP) from the yeast Saccharomyces uvarum was evaluated. The mice were treated with MPs at different doses and times and inoculated with 2% sheep red blood cells. An increase in total Ig in mice treated with 100 μg of MP at the time of immunization or 24 h before was observed in the primary immune response; in the secondary immune response, an increase was observed in total Ig values for all groups, and an increase of IgG was observed in the mice treated with MPs (100 μg) at the time of immunization or 24 h before. These results show that S. uvarum MPs present an immunostimulatory action on the humoral immune response in mice.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000400016
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132012000400016
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.55 n.4 2012
Fonte: | info:eu-repo/semantics/openAccess