Data/hora: 06/06/2024 01:35:55

Provedor de dados: 	52	
País: 	Brazil	
Título: 	Hematological and cerebrospinal fluid changes in cattle naturally and experimentally infected with the bovine herpesvirus 5	
Autores: 	Lisbôa,Júlio Augusto Naylor; Isernhagen,Allan Jürgen; Borges,Alexandre Secorun; Amorim,Rogério Martins; Balarin,Mara Regina Stipp; Lunardi,Michele; Alfieri,Amauri Alcindo.	
Data: 	2009-11-01	
Ano: 	2009	
Palavras-chave: 	Bovine; Meningoencephalitis; Herpesviruses; Complete blood count; Cerebrospinal fluid; Diagnosis.	
Resumo: 	Bovine herpesvirus 5 (BoHV-5) meningoencephalitis is one of the main causes of mortality by encephalopathy in Brazilian cattle herds. However, the neurological signs observed are common to several encephalopathies and do not contribute decisively to a diagnosis. In order to verify hematological and cerebrospinal fluid (CSF) changes, blood and CSF samples from naturally and experimentally infected bovines were evaluated. In natural cases (n=17), the samples were collected only once, and in experimental cases (n=7), the samples were sequentially obtained throughout disease progression. While routine methods were used to examine the samples, BoHV-5 infection was confirmed by a PCR assay. Blood analyses did not reveal any consistent hematological alterations and the leukogram results occasionally showed increases in leukocyte and segmented neutrophil. Hyperfibrinogenemia was noted in all experimentally infected calves and in half of the natural cases. Pleocytosis with mononuclear cells was a remarkable finding in CSF collected from both groups of animals and was present even in experimentally infected calves that remained asymptomatic. Therefore, CSF evaluation can be used as an auxiliary method in ante-mortem BoHV-5 diagnosis.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000700010	
Editor: 	Instituto de Tecnologia do Paraná - Tecpar	
Relação: 	10.1590/S1516-89132009000700010	
Formato: 	text/html	
Fonte: 	Brazilian Archives of Biology and Technology  v.52 n.spe 2009	
Fonte: 	info:eu-repo/semantics/openAccess