Data/hora: 11/06/2024 09:13:14

Provedor de dados: | 52
País: | Brazil
Título: | Detection of Lsr2 gene of Mycobacterium leprae in nasal mucus
Autores: | Custodio,Luiz Antonio; Saito,Alexandre; Amarante,Marla Karine; Fujita,Thiago Cezar; Perim,Aparecida de Lourdes; Costa,Ivete Conchon; Felipe,Ionice; Jankevicius,Shiduca Itow.
Data: | 2012-06-01
Ano: | 2012
Palavras-chave: | Mycobacterium leprae; Leprosy; Hanseniase; Nasal mucus; PCR.
Resumo: | In the present study, nasal mucus from patients with leprosy were analyzed by PCR using specific primers for Lsr2 gene of Mycobacterium leprae. The presence of Lsr2 gene in the nasal mucus was detected in 25.80% of patients with paucibacillari leprosy, and 23.07% of contacts. Despite the absence of clinical features in the contact individuals, it was possible to detect the presence of Lsr2 gene in the nasal mucus of these individuals. Therefore, PCR detection of M. leprae targeting Lsr2 gene using nasal mucus samples could contribute to early diagnosis of leprosy.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000300007
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132012000300007
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.55 n.3 2012
Fonte: | info:eu-repo/semantics/openAccess