Data/hora: 01/06/2024 14:32:06

Provedor de dados: | 52
País: | Brazil
Título: | Extracts of red yolk from duck eggs inhibit metastasis of human mammary carcinoma (4T1) cells in mice
Autores: | Qi-bin,Song; Yi,Yao; Wei-guo,Hu; Sheng-hua,Zhang; Xiao-wei,Yan; Rui,Yang.
Data: | 2011-06-01
Ano: | 2011
Palavras-chave: | Duck egg yolk; Extracts; Mammary carcinoma; Metastasis; 4T1 Cells; BALB/c mice.
Resumo: | The aim of the present study was to investigate the in vivo anti-metastatic activity of the red pigments of red yolk eggs laid by the ducks dieting on Potamogeton cripus L on the mammary carcinoma (4T1). The pigments were extracted with petroleum ether and acetone (2:1, v/v). BALB/c mice were divided into three groups (n=6), fed with the extracts at 150 mg/kg body weight (BW)/day (DEYE-H) or at 50 mg/kg BW/day (DEYE-L) and identical buffer without the extract (control group). The extracts were administered for 34 days. The treatment significantly inhibited the growth of orthotopical 4T1 tumour (DEYE-H vs control, 1:2; DEYE-L vs control, 2:3) and reduced the metastasis of tumour in the lungs (DEYE-H vs control, 4:7; DEYE-L vs control, 5:7), without statistical difference of body weight among the three groups.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000300011
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132011000300011
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.54 n.3 2011
Fonte: | info:eu-repo/semantics/openAccess