Data/hora: 05/06/2024 13:22:11

Provedor de dados: | 52
País: | Brazil
Título: | Experimental models using radionuclides for assessment of the effects of natural drugs
Autores: | Moreno,Silvana Ramos Farias; Carvalho,Jorge José de; Rebello,Bernardo; Rocha,Emely Kazan; Timóteo,Margareth de Oliveira; Olej,Beni; Bernardo Filho,Mário; Caldas,Luiz Querino de Araújo.
Data: | 2008-12-01
Ano: | 2008
Palavras-chave: | Nectandra membranacea (N. membranacea); Ginkgo biloba (EGb); Passiflora edulis flavicarpa (PEF); Blood constituents (BC) labeling; Technetium-99m; Biodistribution.
Resumo: | The aim of this study was to evaluate the effect of the extracts of Nectandra membranacea (N. membranacea), Ginkgo biloba (EGb) and Passiflora (PEF) on the morphology of red blood cells (RBC), on the biodistribution of sodium pertechnetate (99mTcO4Na), on the morphology of duodenum and on the labeling of blood constituents (BC, IF-P, IF-BC) with technetium-99m (Tc-99m). Morphometry studies also were performed. The results show that EGb promotes alteration of the labeling of BC, IF-P and IF-BC (p&lt;0.05). The N. membranacea extract does not promote significant alteration of the radiolabeling, and PEF extract alters the IF-P labeling. N. membranacea, EGb and PEF extracts were able to alter the RBC morphology (P&lt;0.05). N. membranacea extract and EGb modifies the biodistribution of the 99mTcO4Na, and EGb influences the morphometry of duodenum isolated from rats (P&lt;0.05).
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132008000700027
Editor: | Instituto de Tecnologia do Paraná - Tecpar
Relação: | 10.1590/S1516-89132008000700027
Formato: | text/html
Fonte: | Brazilian Archives of Biology and Technology  v.51 n.spe 2008
Fonte: | info:eu-repo/semantics/openAccess