Data/hora: 01/06/2024 01:19:03

Provedor de dados: 	54	
País: 	Brazil	
Título: 	Microphotometric scanning of chromatid gaps and breaks induced by AluI and BamHI in Chinese hamster ovary cells	
Autores: 	Martínez-López,Wilner; Bonomi,Rossana; Folle,Gustavo A.; Drets,Máximo E.	
Data: 	1996-01-01	
Ano: 	1996	
Palavras-chave: 	Microphotometric scanning; Chromatid gaps; AluI; BamHI; Chinese hamster; Ovary cells.	
Resumo: 	Chromatid gaps and breaks induced by the restriction endonucleases AluI and BamHI in the long arm of chromosome 1 of Chinese hamster ovary cells were microphotometrically scanned and mapped to a quantitative G-band map. More than 50% of chromatid breaks appeared as chromatin losses of greater than 5% of the total arm length. The majority of chromatid gaps and breaks as well as chromatin losses induced by both restriction endonucleases were non-randomly located in a region from 0.35 to 0.65 relative length units of the long arm of chromosome 1. We suggest that the access of these endonucleases to chromosomal DNA depends on the local organization of the chromatin.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-84551996000400007	
Editor: 	Sociedade Brasileira de Genética	
Relação: 	10.1590/S0100-84551996000400007	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Genetics  v.19 n.4 1996	
Fonte: 	info:eu-repo/semantics/openAccess