Data/hora: 10/06/2024 08:17:58

Provedor de dados: | 55
País: | Brazil
Título: | Clinical risk factors for Clostridium difficile-associated diseases
Autores: | Cho,Sung Min; Lee,Jae Joon; Yoon,Hee Jung.
Data: | 2012-06-01
Ano: | 2012
Palavras-chave: | Risk factors; Clostridium difficile-associated; Diseases.
Resumo: | Many factors appear to influence the chance of acquiring Clostridium difficile (C. difficile) infection, and an accurate identification of risk factors could be beneficial in many ways. Thus, in the present study, clinical risk factors for C. difficile-associated disease (CDAD) in Korea were identified. A total of 93 patients who met the inclusion criteria and 186 age/gender/ward/admission period-matched control patients were included in this study. Statistically significant associations were found with presence of chronic lung diseases (odds ratio [OR], 3.41; 95% confidence interval [CI], 1.25-9.32; p = 0.017), presence of ileus (OR, 10.05; 95% CI, 2.42-41.80; p = 0.001), presence of intensive care unit (ICU) stay (OR, 9.79; 95% CI, 3.03-31.68; p &lt; 0.001), use of cephalosphorins (OR, 3.30; 95% CI, 1.13-9.62; p = 0.029), history of surgery (OR, 10.89; 95% CI, 3.96-29.92; p &lt; 0.001), and history of long-term care facility stay (OR, 14.90; 95% CI, 4.02-55.26; p &lt; 0.001). Awareness of CDAD is critical to provide appropriate clinical care. Surveillance of the national incidence rate and multicenter studies are needed, and the potential value of a C. difficile vaccine should be studied.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300007
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1590/S1413-86702012000300007
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.16 n.3 2012
Fonte: | info:eu-repo/semantics/openAccess