Data/hora: 11/06/2024 14:52:45

Provedor de dados: 	55	
País: 	Brazil	
Título: 	Ratio of monocytes to lymphocytes in peripheral blood in patients diagnosed with active tuberculosis	
Autores: 	Wang,Jun; Yin,Yongmei; Wang,Xuedong; Pei,Hao; Kuai,Shougang; Gu,Lan; Xing,Huiqin; Zhang,Yu; Huang,Qiusheng; Guan,Bin.	
Data: 	2015-04-01	
Ano: 	2015	
Palavras-chave: 	Active tuberculosis Monocytes Lymphocytes; ML ratio.	
Resumo: 	Objective: The ratio of monocytes to lymphocytes in peripheral blood could reﬂect an indi- vidual's immunity to Mycobacterium tuberculosis . The objective of this study was to evaluate the relationship between ratio of monocytes to lymphocytes and clinical status of patients with active tuberculosis.  Methods: This was a retrospective review of data collected from the clinical database of The Fifth People's Hospital of Wuxi, Medical College of Jiangnan University. A total of 419 patients who had newly diagnosed active tuberculosis and 108 cases from 419 patients with tuberculosis therapy either near completion or completed were selected. Controls were 327 healthy donors.  Results: Median ratio of monocytes to lymphocytes was 0.36 (IQR, 0.22-0.54) in patients before treatment, and 0.16 (IQR, 0.12-0.20) in controls (p &lt; 0.001). Ratio of monocytes to lymphocytes &lt;9% or &gt;25% was signiﬁcant predictors for active tuberculosis (OR = 114.73, 95% CI, 39.80-330.71; OR = 89.81, 95% CI, 53.18-151.68, respectively). After treatment, the median ratio of monocytes to lymphocytes recovered to be nearly normal. Compared to other patients, patients with extrapulmonary tuberculosis and of age &gt;60 years were more likely to have extreme ratio of monocytes to lymphocytes (AOR = 2.57, 95% CI, 1.08-6.09; AOR = 4.36, 95% CI, 1.43-13.29, respectively).  Conclusions: Ratio of monocytes to lymphocytes &lt;9% or &gt;25% is predictive of active tuberculosis.	
Tipo: 	Info:eu-repo/semantics/article	
Idioma: 	Inglês	
Identificador: 	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000200125	
Editor: 	Brazilian Society of Infectious Diseases	
Relação: 	10.1016/j.bjid.2014.10.008	
Formato: 	text/html	
Fonte: 	Brazilian Journal of Infectious Diseases  v.19 n.2 2015	
Fonte: 	info:eu-repo/semantics/openAccess