Data/hora: 02/06/2024 11:31:49

Provedor de dados: | 55
País: | Brazil
Título: | Emergence of colistin resistance in the largest university hospital complex of São Paulo, Brazil, over five years
Autores: | Rossi,Flávia; Girardello,Raquel; Cury,Ana Paula; Di Gioia,Thais Sabato Romano; Almeida Jr,João Nóbrega de; Duarte,Alberto José da Silva.
Data: | 2017-02-01
Ano: | 2017
Palavras-chave: | Colistin-resistant; Polymyxin B-resistant; Enterobacteriaceae; Brazil.
Resumo: | Abstract Colistin resistance involving Gram-negative bacilli infections is a challenge for health institutions around of the world. Carbapenem-resistance among these isolates makes colistin the last therapeutic option for this treatment. Colistin resistance among Enterobacteriaceae, Acinetobacter spp., and Pseudomonas spp. was evaluated between 2010 and 2014 years, at Hospital das Clínicas, São Paulo, Brazil. Over five years 1346 (4.0%) colistin resistant Gram-negative bacilli were evaluated. Enterobacteriaceae was the most frequent (86.1%) pathogen isolated, followed by Acinetobacter spp. (7.6%), and Pseudomonas spp. (6.3%). By temporal analysis there was a trend for an increase of colistin resistance among Enterobacteriaceae, but not among non-fermentative isolates. Among 1346 colistin resistant isolates, carbapenem susceptibility was observed in 21.5%. Colistin resistance in our hospital has been alarmingly increased among Klebsiella pneumoniae isolates in both KPC positive and negative, thus becoming a therapeutic problem.
Tipo: | Info:eu-repo/semantics/other
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100098
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2016.09.011
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.21 n.1 2017
Fonte: | info:eu-repo/semantics/openAccess