Data/hora: 02/06/2024 08:44:05

Provedor de dados: | 55
País: | Brazil
Título: | MRSA from Santa Catarina State, Southern Brazil: intriguing epidemiological differences compared to other Brazilian regions
Autores: | Silveira,Alessandro C.O.; Cunha,Gabriela R.; Caierão,Juliana; Cordova,Caio M. de; d'Azevedo,Pedro A.
Data: | 2015-08-01
Ano: | 2015
Palavras-chave: | Antimicrobial resistance; Vancomycin; Oxacillin.
Resumo: | Methicillin-resistant Staphylococcus aureus(MRSA) is one of the most frequently isolated agents in both nosocomial and community settings. It is a constant challenge for antibacterial therapy. Therefore, it becomes essential to understand the epidemiology of MRSA isolates in the institution and/or region to guide empirical therapy. The objective of this study was to evaluate the epidemiological characteristics of MRSA isolates in the state of Santa Catarina, Brazil, and determine if there is a clonal spread. We evaluated 124 clinical isolates of MRSA obtained from various anatomical sites from patients in the state of Santa Catarina in Southern Brazil. The antimicrobial susceptibility proﬁle was evaluated by disk diffusion and minimum inhibitory concentration (MIC) was determined by Etest and broth macrodilution. SCCmectypes were determined by multiplex PCR and the clonal relationship among isolates was assessed by pulsed ﬁeld gel electrophoresis. Antimicrobials that have demonstrated lower rates of resistance were tetracycline (20.2%), sulfamethoxazole-trimethoprim (20.2%) and chloramphenicol (12.9%). We did not detect any resistance to glycopeptides, daptomycin, linezolid, and tigecycline. SCCmectype III was predominant (54%), followed by type II (21.8%), consistent with other Brazilian studies. Twenty-six clones were observed grouping 72 (58%) isolates and no clonal relationship was observed between our isolates and the major epidemic clones circulating in Brazil. An intriguing distinct MRSA epidemiology was observed in Santa Catarina, compared to other Brazilian regions.
Tipo: | Info:eu-repo/semantics/article
Idioma: | Inglês
Identificador: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400384
Editor: | Brazilian Society of Infectious Diseases
Relação: | 10.1016/j.bjid.2015.04.009
Formato: | text/html
Fonte: | Brazilian Journal of Infectious Diseases  v.19 n.4 2015
Fonte: | info:eu-repo/semantics/openAccess